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Related Concept Videos

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
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Alzheimer Disease l: Introduction

Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
Dementia l: Introduction01:22

Dementia l: Introduction

Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
Dementia01:30

Dementia

Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual.

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Updated: Jun 13, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
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Headache in the elderly: primary forms.

Maria Clara Tonini1, Gennaro Bussone

  • 1Department of Neurology, G. Salvini Hospital, Viale Forlanini 121, 20020, Garbagnate Milanese (MI), Italy. mariaclara.tonini@tin.it

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
|May 14, 2010
PubMed
Summary
This summary is machine-generated.

Diagnosing primary headaches in elderly patients is complex due to comorbidities and medication overuse. This review covers epidemiology, clinical features, and treatments for headaches in older adults.

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Area of Science:

  • Geriatric Medicine
  • Neurology
  • Headache Medicine

Background:

  • Headaches in elderly patients often present diagnostic challenges.
  • Chronic comorbidities and medication overuse complicate headache management in this population.

Purpose of the Study:

  • To review epidemiologic data for primary headaches in the elderly.
  • To outline clinical characteristics of headaches in older adults.
  • To discuss current treatment options for primary headaches in the elderly.

Main Methods:

  • Literature review of epidemiologic data.
  • Analysis of clinical characteristics reported in studies.
  • Synthesis of treatment strategies for primary headaches.

Main Results:

  • Primary headaches in the elderly can mimic symptomatic headaches.
  • Comorbidities and analgesic overuse frequently complicate diagnosis and treatment.
  • Specific epidemiologic data and clinical presentations are discussed.

Conclusions:

  • Accurate diagnosis of primary headaches in the elderly requires careful consideration of complicating factors.
  • Management strategies must address comorbidities and medication overuse.
  • Further research into tailored treatments for elderly headache patients is warranted.