Related Experiment Video
Updated: Jun 13, 2026
10:39
3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
New acute treatments for headache
1The David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. alanrapoport@gmail.com
Summary
New acute migraine treatments are emerging to improve patient care. These include CGRP antagonists and novel delivery systems for existing medications, aiming for faster, more complete, and safer relief.
Area of Science:
- Neurology
- Pharmacology
- Headache Medicine
Background:
- Current acute migraine treatments offer suboptimal control for many patients.
- Patients desire faster onset, more complete relief, reduced recurrence, and fewer adverse events.
Purpose of the Study:
- To review novel and anticipated acute care medications for migraine treatment.
- To discuss emerging therapeutic options beyond current standards of care.
Main Methods:
- Literature review of new and upcoming acute migraine therapies.
- Discussion of specific agents including CGRP antagonists, novel sumatriptan formulations, inhaled dihydroergotamine, and diclofenac potassium.
Main Results:
- Several new acute migraine treatments are in development or recently introduced.
- These include calcitonin gene-related peptide (CGRP) antagonists.
- Novel formulations and delivery methods for existing drugs (sumatriptan, DHE) and new agents (diclofenac potassium) offer improved patient-centric benefits.
Conclusions:
- Emerging acute migraine therapies hold promise for improved patient outcomes.
- These advancements address unmet needs for faster, more effective, and better-tolerated migraine relief.
- While not the focus, preventive treatments like botulinum toxin are also evolving.
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