Increased drug use and STI risk with injection drug use among HIV-seronegative heterosexual methamphetamine users

W Susan Cheng1, Richard S Garfein, Shirley J Semple

  • 1Native American Alliance for Emergency Preparedness (NAAEP), California Department of Health Care Services, Davis, CA, USA.

Insights

Methamphetamine injectors face higher HIV and STI risks than non-injectors. Tailored prevention for methamphetamine users is crucial based on administration method.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Addiction Medicine

Background:

  • Methamphetamine (MA) use is linked to increased HIV and sexually transmitted infection (STI) risks, particularly among men who have sex with men.
  • Limited data exist on whether injecting MA (IDU) poses a greater risk than other administration routes.
  • Comparable data for heterosexual MA users are lacking.

Purpose of the Study:

  • To investigate if HIV and STI risks differ between heterosexual MA users who inject MA and those who do not.
  • To identify factors associated with injecting MA among heterosexual users.

Main Methods:

  • Cross-sectional study interviewing 452 HIV-negative heterosexual MA users (aged 18+) between 2001-2005.
  • Participants reported recent MA use and unprotected sex.
  • Logistic regression analysis identified factors associated with MA injection.

Main Results:

  • Injecting MA users (IDU) were more likely to be Caucasian, homeless, have longer MA use history, and report recent STIs compared to non-IDU.
  • IDU also reported using more grams of MA in the last 30 days and had a history of felony conviction.
  • Recent STI diagnosis was significantly associated with MA injection.

Conclusions:

  • MA injection is associated with higher HIV and STI risks among heterosexual users.
  • Prevention interventions for MA users should be tailored based on their method of administration (injection vs. non-injection).

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