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Medical complaints are more common in young school-aged children with parent reported insomnia symptoms
Ravi Singareddy1, Sumana Moole, Susan Calhoun
1Sleep Research & Treatment Center, Department of Psychiatry, Penn State College of Medicine, Hershey, PA 17033, USA. rsingareddy@psu.edu
Insights
Children with insomnia symptoms frequently experience gastrointestinal issues and headaches. This highlights the need to consider sleep problems when diagnosing medical complaints in children.
Area of Science:
- Pediatric Sleep Medicine
- Child Neurology
- Pediatric Gastroenterology
Background:
- Sleep disturbances are linked to medical issues in adults, but research in children is limited.
- Few studies have investigated the prevalence of medical complaints in children experiencing insomnia symptoms within a general population sample.
Purpose of the Study:
- To examine the prevalence of medical complaints in school-aged children with insomnia symptoms.
- To explore the association between insomnia symptoms and specific medical complaints in a pediatric cohort.
Main Methods:
- A cross-sectional study involving 700 children (ages 5-12) from the Penn State Children's Cohort.
- Data collection included medical/psychiatric history, physical examination, polysomnography, neuropsychological testing, and parent-completed questionnaires.
- Comparison between 135 children with sleep disturbances and 565 without.
Main Results:
- Insomnia symptoms were significantly associated with gastrointestinal regurgitation (OR 3.3) and headaches (OR 2.3) in children.
- These associations remained significant after controlling for demographic, psychiatric, and sleep-related variables.
- Children with sleep disturbances showed objectively increased sleep latency and differences in REM latency and sleep stages.
Conclusions:
- Inquiring about insomnia is crucial for children presenting with gastrointestinal issues or headaches.
- A comprehensive medical history is essential when children exhibit sleep complaints.
- Further research is needed to understand the pathophysiology of insomnia and medical symptom comorbidity in children.
Objective:
Studies in adults have found significant association between sleep disturbances and various medical symptoms/disorders. However, in children, few studies have explored this complex association in clinical samples. In this study, we examined prevalence of medical complaints in children with insomnia symptoms in a large general population of school aged children.
Methods:
We conducted a cross sectional study of 700 children, ages 5-12 years, from the Penn State Children's Cohort. All children underwent a medical and psychiatric history, physical examination, 9-h overnight polysomnography, and neuropsychological testing. Comprehensive sleep and development questionnaires were completed by a parent. We compared 135 (19.3%) children with parent-reported sleep disturbances to 565 (80.7%) children with no parent-reported sleep disturbances.
Results:
Insomnia symptoms were significantly associated with gastrointestinal regurgitation and headaches after controlling for demographic variables, apnea hypopnea index, ADHD, learning disorder or other psychiatric/behavioral disorder, socioeconomic status, and minority status. Children with gastrointestinal regurgitation and headaches compared to children without these symptoms were 3.3 times and 2.3 times as likely to suffer from sleep disturbances, respectively. Objectively, sleep latency increased in the sleep disturbance group, and there were significant differences between groups in REM latency, slow wave, and stage 2 sleep.
Discussion:
These results underscore the importance of inquiring about insomnia symptoms when children present with medical complaints particularly gastrointestinal regurgitation or headaches and taking a comprehensive medical history when children present with sleep complaints. Future studies are needed to replicate these findings and explore the possible underlying pathophysiological abnormalities of such comorbidity between insomnia symptoms and medical symptoms in children.
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