Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 13, 2026

Fabricating High-viscosity Droplets using Microfluidic Capillary Device with Phase-inversion Co-flow Structure

Fabricating High-viscosity Droplets using Microfluidic Capillary Device with Phase-inversion Co-flow Structure

Published on: April 17, 2018

Hysteresis in multiphase microfluidics at a T-junction.

Michele Zagnoni¹, Jamie Anderson, Jonathan M Cooper

¹Department of Electronics and Electrical Engineering, University of Glasgow, G12 8LT, United Kingdom. M.Zagnoni@elec.gla.ac.uk

Langmuir : the ACS Journal of Surfaces and Colloids

|May 15, 2010

Summary

Multiphase microfluidics exhibit hysteresis in hydrophilic T-junctions, producing distinct flow patterns based on flow rate history. This behavior enables applications in pressure comparison and microfluidic logic operations.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Dielectric levitation optical tweezers for powerful mesoscale biomanipulation.

Proceedings of the National Academy of Sciences of the United States of America·2026

Same author

Examining the effectiveness of financial vs. social incentives to participate in a smartphone ecological momentary assessment well-being study: protocol for a randomized controlled trial.

Frontiers in digital health·2026

Same author

Knowledge acquisition and retention when implementing public health awareness training on common pediatric eye conditions in Thailand.

Global health journal (Amsterdam, Netherlands)·2026

Same author

Incorporating real-world scenarios during initial validation stages of point-of-care human papillomavirus (HPV) screening tests: a scoping review.

Sexually transmitted infections·2026

Same author

Corrigendum to 'Multiomic, Histologic, and scRNA-seq Profiling of Pleural Mesothelioma Reveals Negative Prognosis Associated With a Novel Uncommitted Molecular Phenotype' [Journal of Thoracic Oncology Volume 21 Issue 4 (2026) 103529].

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer·2026

Same author

Long-term impacts of co-designed sustainable park improvements on physical activity and other wellbeing behaviours: a 7-year natural experimental study in a deprived urban area.

The international journal of behavioral nutrition and physical activity·2026

Area of Science:

Fluid dynamics
Microfluidics
Biotechnology

Background:

Multiphase microfluidics are versatile tools in fluid dynamics, biology, and particle synthesis.
Recent advancements show potential for multiphase microfluidics in logical computation.

Purpose of the Study:

To investigate the hysteresis phenomenon in immiscible multiphase flow within hydrophilic microfluidic systems.
To analyze the transition mechanisms between different flow patterns.

Main Methods:

Experimental analysis of oil-water flow at a T-junction.
Numerical simulations to model fluid dynamic parameters and hysteresis.

Main Results:

Reliable production of stable and unstable flow patterns (segmented and parallel) based on flow rate history.

More Related Videos

Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions

Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions

Published on: April 19, 2018

Analyzing Mixing Inhomogeneity in a Microfluidic Device by Microscale Schlieren Technique

Analyzing Mixing Inhomogeneity in a Microfluidic Device by Microscale Schlieren Technique

Published on: June 12, 2015

Related Experiment Videos

Last Updated: Jun 13, 2026

Fabricating High-viscosity Droplets using Microfluidic Capillary Device with Phase-inversion Co-flow Structure

Fabricating High-viscosity Droplets using Microfluidic Capillary Device with Phase-inversion Co-flow Structure

Published on: April 17, 2018

Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions

Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions

Published on: April 19, 2018

Analyzing Mixing Inhomogeneity in a Microfluidic Device by Microscale Schlieren Technique

Analyzing Mixing Inhomogeneity in a Microfluidic Device by Microscale Schlieren Technique

Published on: June 12, 2015

Identification of physical and fluid dynamic parameters influencing hysteretic behavior.

Conclusions:

The observed hysteresis in multiphase microfluidic flow is controllable via flow rates.
These systems are suitable for pressure comparators and microfluidic logic gate implementation.