Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Revealing the Hidden Tube: A Simple Laser Solution in a Complex Eye.

Ophthalmology. Glaucoma·2026
Same author

Impact of Cataract Surgery on Psychological Well-Being and Economy: The SCOPE Study Protocol.

Ophthalmic epidemiology·2026
Same author

Rho-kinase inhibitors predisposing to secondary keratitis.

BMJ case reports·2026
Same author

Allergic eye disease in clinical practice: essential updates for eye care professionals.

Clinical & experimental optometry·2026
Same author

Diffuse Choroidal Hemangioma in Sturge-Weber Syndrome: Correlation between Clinical Features, Imaging, and Treatment Response.

Ocular oncology and pathology·2026
Same author

Long-term Clinical Outcomes of Type 1 Keratoprosthesis: A 10-Year Experience.

Cornea·2026

Related Experiment Video

Updated: Jun 13, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

Angle closure in the Andhra Pradesh Eye Disease Study.

Sirisha Senthil1, Chandrasekhar Garudadri, Rohit C Khanna

  • 1L.V Prasad Eye Institute, Kallam Anji Reddy campus, L.V Prasad Marg, Banjara Hills, Hyderabad, India. siddharth142@sify.com

Ophthalmology
|May 15, 2010
PubMed
Summary

Primary angle-closure glaucoma (PACG) affects 0.94% of adults in Andhra Pradesh, India. Key risk factors include increasing age, elevated intraocular pressure, diabetes, and female gender, with 20% experiencing blindness.

Related Experiment Videos

Last Updated: Jun 13, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

Area of Science:

  • Ophthalmology
  • Public Health
  • Epidemiology

Background:

  • Primary angle-closure glaucoma (PACG) is a leading cause of irreversible blindness globally.
  • Understanding the prevalence and risk factors of PACG is crucial for targeted public health interventions.
  • Previous epidemiological data on PACG in specific Indian populations remain limited.

Purpose of the Study:

  • To determine the prevalence of primary angle-closure glaucoma (PACG), primary angle closure (PAC), and primary angle-closure suspects (PACS) in Andhra Pradesh, India.
  • To identify associated risk factors for angle-closure disease (ACD) in this population.
  • To assess the level of awareness regarding ACD among affected individuals.

Main Methods:

  • A population-based, cross-sectional study was conducted between 1996 and 2000.
  • A stratified, random, cluster, and systematic sampling strategy included 3724 participants aged 40 years and older from urban and rural areas.
  • Comprehensive eye examinations were performed, including gonioscopy and visual field testing when indicated.

Main Results:

  • The age- and gender-adjusted prevalence of PACG was 0.94%, PAC was 0.3%, and PACS was 2.0%.
  • The overall prevalence of angle-closure disease (PACG + PAC) was 1.26%.
  • Eighty-seven percent of individuals with ACD were unaware of their condition. Significant risk factors included increasing age, elevated intraocular pressure (IOP), diabetes mellitus, and female gender. Twenty percent of PACG patients were blind.

Conclusions:

  • The prevalence of PACG in the studied population of Andhra Pradesh is 0.94%.
  • Increasing age, elevated IOP, diabetes mellitus, and female gender are significant risk factors associated with angle-closure disease.
  • A high proportion (20%) of PACG cases resulted in blindness, highlighting the need for early detection and management.