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Updated: Jun 13, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Special considerations in pediatric asthma.

Annabelle Quizon¹, Andrew A Colin

¹University of Miami-Miller School of Medicine, Department of Pediatrics, Division of Pediatric Pulmonology, 1st Floor, Batchelor Children's Research Institute, 1580 NW 10th Avenue, Miami, FL 33136, United States. aquizon@med.miami.edu

Current Opinion in Pharmacology

|May 15, 2010

Summary

This summary is machine-generated.

Childhood asthma management focuses on effective interventions and safe controller medications. Inhaled corticosteroids (ICS) are effective but do not alter asthma progression; lowest effective doses minimize risks.

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Last Updated: Jun 13, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Area of Science:

Pediatric Pulmonology
Allergy and Immunology
Clinical Pharmacology

Background:

Asthma is a prevalent chronic childhood illness.
Interventions aim to alter disease course and address medication safety concerns.
Inhaled corticosteroids (ICS) are common controller medications.

Purpose of the Study:

Review the efficacy and safety of ICS in children.
Explore the use of as-needed ICS for risk reduction in mild persistent asthma.
Discuss updated asthma management guidelines and other interventions.

Main Methods:

Literature review of recent studies on ICS use in children.
Analysis of safety and efficacy data for inhaled corticosteroids.
Examination of National Institutes of Health (NIH) asthma guidelines (2007).

Main Results:

ICS are effective for symptom control but do not alter long-term asthma progression in very young children.
Titrating ICS to the lowest effective dose is key for risk reduction.
Other strategies include allergen avoidance, obesity management, and appropriate inhaler devices.

Conclusions:

Optimizing ICS dosage and considering alternative strategies are crucial for managing childhood asthma.
Updated guidelines emphasize a comprehensive approach beyond medication alone.
Environmental factors and patient adherence are vital for effective asthma control.