Related Experiment Videos
Activity of aniline in the mouse bone marrow micronucleus assay
J Ashby1, D A Vlachos, H Tinwell
1ICI Central Toxicological Laboratory, Alderley Park, Macclesfield, Great Britain.
Mutation Research
|June 1, 1991
Abstract:
Aniline gave a positive response in the mouse bone marrow micronucleus assay 24 h after the second of two intraperitoneal injections of 80% of the median lethal dose (MLD). Negative results were observed at lower dose levels and at earlier and later sampling times. The significance of this unique activity profile is discussed within the context of the non-carcinogenicity of aniline to the mouse.