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Related Experiment Video

Updated: Jun 13, 2026

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping

Published on: September 25, 2019

Incomplete brain infarction.

Yuichiro Inatomi¹, Toshiro Yonehara, Teruyuki Hirano

¹Department of Neurology, Stroke Center, Saiseikai Kumamoto Hospital. y.inatomix@silk.ocn.ne.jp

Internal Medicine (Tokyo, Japan)

|May 15, 2010

Summary

This summary is machine-generated.

Incomplete infarction can cause critical brain lesions without complete infarction. Technetium-99m-ECD SPECT imaging detected these lesions when MRI was unclear, aiding diagnosis.

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Area of Science:

Neurology
Radiology
Nuclear Medicine

Background:

Diagnosing incomplete infarction can be challenging with conventional imaging like MRI.
Early detection of ischemic brain lesions is crucial for timely intervention.

Observation:

A 70-year-old man experienced two episodes suggestive of incomplete infarction.
Initial MRI (including Diffusion-Weighted Imaging - DWI) was inconclusive for the first event.
Technetium-99m-Ethylcysteinate Dimer (99mTc-ECD) SPECT showed high uptake in the acute phase of the first attack.
The lesion became atrophic with low SPECT uptake in the chronic phase.
The second attack showed subtle DWI hyperintensities but was better visualized with SPECT and angiography.
Angiography revealed capillary blush during the acute phase of the second attack.

Findings:

99mTc-ECD SPECT effectively identified acute ischemic lesions not clearly seen on DWI.
Incomplete infarction alone can lead to significant and clinically critical brain damage.
Lesion characteristics on SPECT evolved from acute (high uptake) to chronic (low uptake).

Implications:

99mTc-ECD SPECT may be a valuable tool for diagnosing incomplete infarction when MRI is equivocal.
This case highlights the potential severity of incomplete infarcts, emphasizing the need for accurate diagnostic methods.
Understanding the imaging characteristics of incomplete infarction can improve patient management and outcomes.