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Growth and nutrition in children with chronic kidney disease

D H Chand1, V S Vitale

  • 1Division of Nephrology and Hypertension, Akron Children's Hospital, Akron, OH 44308, USA. dchand@chmca.org

Minerva Pediatrica
|May 15, 2010
PubMed

Insights

Children with chronic kidney disease (CKD) experience growth failure from factors like anemia and metabolic acidosis. Optimizing treatment for these issues is crucial for improving health outcomes in pediatric CKD patients.

Area of Science:

  • Pediatric Nephrology
  • Growth and Development in Chronic Illness

Background:

  • Children with chronic kidney disease (CKD) frequently exhibit impaired growth.
  • Multiple factors contribute to growth failure, including nutritional deficits, metabolic acidosis, anemia, and growth hormone resistance.

Purpose of the Study:

  • To highlight the multifactorial nature of growth failure in pediatric CKD.
  • To emphasize the importance of addressing key variables in managing these patients.

Main Methods:

  • Review of contributing factors to growth failure in pediatric chronic kidney disease.
  • Analysis of the impact of nutritional deficiencies, metabolic acidosis, anemia, and growth hormone resistance.

Main Results:

  • Each identified factor (nutritional deficiencies, metabolic acidosis, anemia, growth hormone resistance) independently exacerbates morbidity and mortality.
  • Psychosocial well-being is also negatively impacted in children with CKD.

Conclusions:

  • Comprehensive management by nephrology teams is essential to optimize treatment of contributing factors.
  • Addressing these variables is critical for improving growth and overall health in pediatric CKD patients.

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