Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Introduction to Stress and Lifestyle01:27

Introduction to Stress and Lifestyle

Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...
Physiological Foundation of Stress01:24

Physiological Foundation of Stress

Stress triggers a coordinated physiological response involving the sympathetic nervous system (SNS) and the hypothalamic-pituitary-adrenal (HPA) axis. This dual activation ensures that the body is prepared for both immediate and prolonged stress management. The process begins with the perception of a stressor. This initial phase activates the SNS, leading to the rapid release of adrenaline (epinephrine) from the adrenal glands.
Role of the Sympathetic Nervous System
Adrenaline triggers the...
Psychological Responses to Stress01:20

Psychological Responses to Stress

Psychological responses to stress encompass the various cognitive and emotional reactions individuals experience when faced with challenging or threatening situations, such as a job loss. Prolonged exposure to stressors can disturb emotional balance, increasing negative emotions (e.g., anxiety and sadness) and diminishing positive emotions (e.g., joy and satisfaction). These persistent emotional shifts are associated with an increased risk of both physical illness and mental health issues, such...
Stress01:20

Stress

When a force is applied on a body, it undergoes deformation. In order to restore the body to its original shape and/or size, an opposite or restoring force is generated within the body. This restoring force is equal to the magnitude of the applied force, but acts in the opposite direction. The amount of this restoring force developed per unit area of the body is called stress. Stress is a tensor quantity and has the SI unit pascal. Stress can be separated into four broad categories depending...
Types of Stressors01:23

Types of Stressors

A stressor is any event, condition, or stimulus that triggers stress and causes a physical or psychological response in the body. Stressors can be categorized into three main types: catastrophes; significant life changes; and daily hassles, including social stress. Each can be detrimental to physical and mental well-being.
Catastrophes
Catastrophes refer to large-scale, unpredictable events that create overwhelming stress and a sense of threat. Examples include natural disasters like...
Hypothalamic-Pituitary Axis01:37

Hypothalamic-Pituitary Axis

The response to stress—be it physical or psychological, acute or chronic—involves activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is part of the neuroendocrine system because it involves both neuronal and hormonal communication. Its function is to regulate homeostatic systems—metabolic, cardiovascular, and immune—providing the necessary means to respond to a stressor.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Clinical emergency-complicated infections of the middle ear and paranasal sinuses].

HNO·2026
Same author

Suicidal ideation in patients with skin conditions: A multicentre European study.

Journal of the European Academy of Dermatology and Venereology : JEADV·2026
Same author

Is Vitamin D Signaling Regulated by and Does It Regulate Circadian Rhythms?

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2025
Same author

A cross-sectional study on gender differences in body dysmorphic concerns in patients with skin conditions in relation to sociodemographic, clinical and psychological variables.

Journal of the European Academy of Dermatology and Venereology : JEADV·2024
Same author

Correction to: Comparative Effectiveness and Durability of Biologics in Clinical Practice: Month 12 Outcomes from the International, Observational Psoriasis Study of Health Outcomes (PSoHO).

Dermatology and therapy·2024
Same author

Chronic nodular prurigo: Association between comorbidities, itch and quality of life.

Journal of the European Academy of Dermatology and Venereology : JEADV·2024

Related Experiment Video

Updated: Jun 13, 2026

Thermal Imaging to Study Stress Non-invasively in Unrestrained Birds
10:07

Thermal Imaging to Study Stress Non-invasively in Unrestrained Birds

Published on: November 6, 2015

Stress and the skin.

A Reich1, A Wójcik-Maciejewicz, A T Slominski

  • 1Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Wroclaw, Poland. areich@derm.am.wroc.pl

Giornale Italiano Di Dermatologia E Venereologia : Organo Ufficiale, Societa Italiana Di Dermatologia E Sifilografia
|May 15, 2010
PubMed
Summary

Emotional stress impacts skin health, potentially worsening conditions like psoriasis and eczema. Emerging evidence suggests stress triggers inflammation via the hypothalamic-pituitary-adrenal axis and neuro-immune interactions.

More Related Videos

The Trier Social Stress Test Protocol for Inducing Psychological Stress
09:39

The Trier Social Stress Test Protocol for Inducing Psychological Stress

Published on: October 19, 2011

Related Experiment Videos

Last Updated: Jun 13, 2026

Thermal Imaging to Study Stress Non-invasively in Unrestrained Birds
10:07

Thermal Imaging to Study Stress Non-invasively in Unrestrained Birds

Published on: November 6, 2015

The Trier Social Stress Test Protocol for Inducing Psychological Stress
09:39

The Trier Social Stress Test Protocol for Inducing Psychological Stress

Published on: October 19, 2011

Area of Science:

  • Dermatology
  • Psychoneuroimmunology
  • Skin Biology

Background:

  • Emotional stress is increasingly recognized as a factor in various skin disorders.
  • The precise mechanisms linking stress to skin conditions remain incompletely understood.
  • Existing research suggests stress impacts disease processes and inflammation.

Purpose of the Study:

  • To explore the intricate relationship between emotional stress and skin disorders.
  • To review the current understanding of the pathophysiological pathways involved.
  • To highlight the interconnectedness of the skin, endocrine, nervous, and immune systems.

Main Methods:

  • Review of existing scientific literature on stress and dermatology.
  • Analysis of proposed pathophysiological mechanisms.
  • Discussion of cellular and systemic responses to stress in the skin.

Main Results:

  • Stress influences disease processes and inflammation through the hypothalamic-pituitary-adrenal axis.
  • Dermal mast cells play a key role in cellular skin reactivity to stressors.
  • Neuropeptides, neurotrophins, and lymphokines are implicated in stress-induced skin responses.

Conclusions:

  • The skin, endocrine, nervous, and immune systems are interconnected and cannot be viewed in isolation.
  • Stress significantly contributes to the pathogenesis and exacerbation of numerous skin disorders.
  • Further research is needed to fully elucidate the complex interactions within this neuro-immuno-cutaneous axis.