Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Exercise and Muscle Performance

Exercise and Muscle Performance

Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...

The Blood-brain Barrier

The Blood-brain Barrier

Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

Neurogenesis and Regeneration of Nervous Tissue

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Response.

Medicine and science in sports and exercise·2026

Same author

Ultra-endurance race performance and muscle mass as predictors of cognitive capacity.

Frontiers in cognition·2026

Same author

Comparing embedded virtual reality combat to traditional warm-ups on fencing performance and fatigue: Protocol for a randomized crossover trial.

JSAMS plus·2026

Same author

Brain resting state functional connectivity changes with aerobic exercise, and mindfulness: A narrative review.

Sports medicine and health science·2026

Same author

Handgrip performance as a predictor of incident cognitive decline in older adults: A systematic review and meta-analysis.

Neuroscience and biobehavioral reviews·2026

Same author

Influence of a passive shoulder exoskeleton on drilling performance in women- a cross-sectional study.

Scientific reports·2026

Search research articles

Related Experiment Video

Updated: Jun 13, 2026

Orienteering as a Tool for Cognitive Research: An Implementation Guide

Orienteering as a Tool for Cognitive Research: An Implementation Guide

Published on: November 29, 2024

Strength training does not influence serum brain-derived neurotrophic factor.

Maaike Goekint¹, Kevin De Pauw, Bart Roelands

¹Department of Human Physiology and Sports Medicine, Faculty of Physical Education and Physical Therapy, Vrije Universiteit Brussel, Brussels, Belgium.

European Journal of Applied Physiology

|May 15, 2010

Summary

A 10-week strength training program did not significantly alter brain-derived neurotrophic factor (BDNF) or insulin-like growth factor-1 (IGF-1) levels or memory function in sedentary individuals. Acute training sessions also showed no immediate impact on these growth factors.

More Related Videos

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

Published on: July 5, 2017

Treatment of Ligament Constructs with Exercise-conditioned Serum: A Translational Tissue Engineering Model

Treatment of Ligament Constructs with Exercise-conditioned Serum: A Translational Tissue Engineering Model

Published on: June 11, 2017

Related Experiment Videos

Last Updated: Jun 13, 2026

Orienteering as a Tool for Cognitive Research: An Implementation Guide

Orienteering as a Tool for Cognitive Research: An Implementation Guide

Published on: November 29, 2024

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

Published on: July 5, 2017

Treatment of Ligament Constructs with Exercise-conditioned Serum: A Translational Tissue Engineering Model

Treatment of Ligament Constructs with Exercise-conditioned Serum: A Translational Tissue Engineering Model

Published on: June 11, 2017

Area of Science:

Exercise Physiology
Neuroscience
Biochemistry

Background:

Brain-derived neurotrophic factor (BDNF) and insulin-like growth factor-1 (IGF-1) are crucial for neuronal plasticity and cognitive function.
Understanding how strength training influences these factors and memory is important for health and disease management.

Purpose of the Study:

To investigate the acute effects of a single strength training session on BDNF and IGF-1.
To determine the impact of a 10-week strength training program on resting BDNF, IGF-1, and memory performance in untrained individuals.

Main Methods:

Fifteen untrained subjects underwent a 10-week strength training program; eight served as controls.
Blood samples were collected pre- and post-training sessions and pre- and post-program.
Short-term and mid-term memory were assessed using digit span and image recall tests.

Main Results:

A single strength training session did not acutely affect BDNF or IGF-1 levels.
No significant changes in resting BDNF, IGF-1, or IGFBP-3 were observed after 10 weeks of training.
Short-term memory improved in both groups, with no significant difference between them; mid-term memory did not improve.

Conclusions:

A 10-week strength training program does not significantly alter BDNF, IGF-1, or memory function in sedentary individuals compared to inactivity.
Neither acute nor chronic strength training demonstrated a significant impact on the measured growth factors or cognitive functions in this study population.