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Related Concept Videos

Traumatic Brain Injury l: Introduction01:28

Traumatic Brain Injury l: Introduction

DefinitionTraumatic brain injury, or TBI, is a disturbance of normal brain function induced by an external mechanical force, such as a direct blow to the head or a penetrating injury. It can affect both brain structure and function, producing a wide range of clinical outcomes. TBI is a heterogeneous condition, meaning its effects may differ based on the type, location, and severity of the injury.Basis of ClassificationTBI is classified based on severity, injury mechanism, or pathophysiology. In...
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Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

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In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses a challenge in...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...

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Related Experiment Video

Updated: Jun 13, 2026

A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)
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A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)

Published on: February 7, 2025

Pediatric TBI: prevalence and functional ramifications.

Chad A Noggle1, Eric E Pierson

  • 1Department of Educational Psychology, Ball State University, Teachers College, Rm. 524, Muncie, IN 47306, USA. eepierson@bsu.edu

Applied Neuropsychology
|May 15, 2010
PubMed
Summary
This summary is machine-generated.

This special issue introduces the assessment and treatment of traumatic brain injury (TBI) in children and adolescents. Neuropsychologists are uniquely skilled to address TBI

Related Experiment Videos

Last Updated: Jun 13, 2026

A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)
07:01

A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)

Published on: February 7, 2025

Area of Science:

  • Pediatric Neuropsychology
  • Traumatic Brain Injury (TBI) Assessment
  • Child Neuropsychology

Background:

  • Highlights the critical need for specialized assessment and treatment of traumatic brain injury (TBI) in pediatric populations.
  • Emphasizes the multifaceted nature of TBI, requiring consideration beyond injury severity and developmental stage.

Discussion:

  • Integrates the importance of familial and social functioning into the comprehensive evaluation and management of pediatric TBI.
  • Underscores the unique qualifications of neuropsychologists in addressing the psychological and neurocognitive sequelae of TBI in children and adolescents.

Key Insights:

  • Neuropsychologists leverage psychological skills and neurocognitive principles for effective TBI intervention.
  • A holistic approach, encompassing family and social dynamics, is crucial for successful pediatric TBI outcomes.

Outlook:

  • This special issue aims to advance the understanding and application of neuropsychological expertise in pediatric TBI care.
  • Future directions include refining assessment tools and treatment strategies tailored to the developmental needs of children with TBI.