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Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...

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Related Experiment Video

Updated: Jun 13, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
07:36

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

Perinatal death and damage: predictive and preventive considerations.

S B Effer

    Canadian Family Physician Medecin De Famille Canadien
    |May 15, 2010
    PubMed
    Summary
    This summary is machine-generated.

    Identifying and managing high-risk pregnancies is crucial for preventing fetal and newborn death or brain damage. Early detection and intervention strategies are vital for better outcomes in high-risk pregnancies.

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    Related Experiment Videos

    Last Updated: Jun 13, 2026

    Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
    07:36

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    Published on: November 20, 2015

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    Area of Science:

    • Perinatology
    • Maternal-Fetal Medicine
    • Neonatology

    Background:

    • High-risk pregnancies pose significant threats to fetal and newborn well-being.
    • Classical clinical conditions are associated with major risks to the fetus and newborn.

    Purpose of the Study:

    • To review classical clinical entities associated with high-risk pregnancies.
    • To discuss methods for identifying and managing high-risk pregnancies.
    • To emphasize the importance of early detection and intervention for adverse outcomes.

    Main Methods:

    • Review of classical clinical entities and risk factors.
    • Description of statistical systems for high-risk patient identification.
    • Outline of clinical examination techniques for screening feto-placental malfunction.
    • Discussion of sophisticated detection and management methods for high-risk pregnancies.

    Main Results:

    • Identification of high-risk patients can be facilitated by statistical systems and clinical examination.
    • Feto-placental malfunction presents serious risks, exacerbated by labor stress.
    • Catastrophic failures in management can lead to fetal death or brain damage.

    Conclusions:

    • High-risk pregnancies require careful consideration and respect.
    • Cooperative efforts are needed to investigate and implement known measures for improvement.
    • Early and accurate diagnosis of feto-placental malfunction is critical for preventing severe sequelae.