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Hormonal Regulation of the Menstrual Cycle

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Hormonal Regulation

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Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
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Published on: September 16, 2021

Hormonal therapy for suppressing lactation.

H C Balmer, D J Macdonald

    Canadian Family Physician Medecin De Famille Canadien
    |May 15, 2010
    PubMed
    Summary
    This summary is machine-generated.

    Hormonal suppression effectively stops undesired lactation using estrogen or progestogen-estrogen combinations. A new study confirms norethynodrel and mestranol are successful suppressants with low thromboembolism risk.

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    Area of Science:

    • Reproductive endocrinology
    • Pharmacology

    Background:

    • Hormonal therapies are increasingly used to suppress lactation.
    • Estrogen and progestogen-estrogen combinations have demonstrated efficacy.

    Purpose of the Study:

    • To review the literature on hormonal lactation suppression.
    • To evaluate the incidence of thromboembolism associated with these therapies.
    • To report on a new study assessing norethynodrel and mestranol for lactation suppression.

    Main Methods:

    • Literature review of hormonal lactation suppression methods.
    • Analysis of retrospective studies on thromboembolism incidence.
    • Conducting a new double-blind study on norethynodrel and mestranol efficacy.

    Main Results:

    • Hormonal suppression, including estrogen and progestogen-estrogen combinations, is effective.
    • Retrospective data on thromboembolism incidence is discussed.
    • The double-blind study demonstrated successful lactation suppression with norethynodrel and mestranol.

    Conclusions:

    • Hormonal suppression is a viable method for managing undesired lactation.
    • Norethynodrel and mestranol represent a safe and effective option for lactation suppression.