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Related Concept Videos

Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is based on...
Carbohydrate Metabolism01:36

Carbohydrate Metabolism

Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in the...
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis01:25

Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis

Type 2 diabetes mellitus develops gradually and is often asymptomatic in early stages.Clinical ManifestationsWhen symptoms appear, they include fatigue, blurred vision, pruritus, delayed wound healing, and recurrent infections, particularly candidal infections. Peripheral neuropathy may present as numbness or tingling in the extremities. Classic hyperglycemia symptoms—polyuria, polydipsia, and polyphagia—are less common. Most patients are overweight and frequently have associated hypertension...
Insulin: Dosing Regimen and Adverse Effects01:16

Insulin: Dosing Regimen and Adverse Effects

Insulin-replacement therapy usually includes both long-acting insulin (basal) and short-acting insulin (to cater to postprandial needs). In a diverse group of type 1 diabetes patients, the average daily insulin dose is typically 0.5-0.7 units/kg body weight. However, obese patients and pubertal adolescents may need more due to insulin resistance.
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
Type I Diabetes III: Clinical Manifestations01:19

Type I Diabetes III: Clinical Manifestations

Type 1 diabetes mellitus typically presents with rapid-onset symptoms due to the body’s inability to utilize glucose in the absence of insulin. Since insulin is required for glucose uptake into cells, its deficiency leads to hyperglycemia and cellular energy deprivation, resulting in characteristic clinical features.Polyuria and PolydipsiaOne of the earliest, most prominent symptoms is polyuria (excessive urination). When blood glucose concentrations rise above the renal threshold, the kidneys...

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Maternal and neonatal outcomes in pregestational and gestational diabetes mellitus, and the influence of maternal obesity and weight gain: the DEPOSIT study. Diabetes Endocrine Pregnancy Outcome Study in Toronto.

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Randomized Controlled Trial to Study the Acute Effects of Strength Exercise on Insulin Sensitivity in Obese Adults
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Published on: December 1, 2023

Weight in diabetes.

A B Kenshole

    Canadian Family Physician Medecin De Famille Canadien
    |May 15, 2010
    PubMed
    Summary
    This summary is machine-generated.

    Obesity is linked to a rising number of diabetes cases. Effective weight reduction strategies are crucial for managing and potentially preventing type 2 diabetes in overweight individuals.

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    Area of Science:

    • Endocrinology
    • Metabolic Disorders
    • Public Health

    Background:

    • Increasing prevalence of overweight and obesity globally.
    • Strong correlation observed between excess body weight and the incidence of diabetes mellitus.
    • Obesity as a significant risk factor for developing type 2 diabetes.

    Purpose of the Study:

    • To elucidate the intricate relationship between diabetes and obesity.
    • To review and present effective weight reduction methodologies for overweight individuals.
    • To provide insights into managing diabetes through weight control.

    Main Methods:

    • Literature review of studies on diabetes and obesity.
    • Analysis of epidemiological data linking weight status to diabetes diagnosis.
    • Synthesis of evidence-based strategies for weight management.

    Main Results:

    • Confirmed significant association between higher Body Mass Index (BMI) and increased diabetes risk.
    • Identified various successful weight reduction interventions, including dietary changes, physical activity, and behavioral therapy.
    • Demonstrated that substantial weight loss can improve glycemic control and reduce diabetes complications.

    Conclusions:

    • Weight reduction is a key therapeutic and preventative strategy for diabetes in overweight populations.
    • Comprehensive lifestyle interventions are essential for achieving and maintaining satisfactory weight loss.
    • Further research into personalized weight management programs for diabetes prevention and treatment is warranted.