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Hyperglycemia

Hyperglycemia

Hyperglycemia is an abnormally high blood glucose level. It is diagnosed by fasting glucose ≥126 mg/dL, 2-hour oral glucose tolerance test (or OGTT) ≥200 mg/dL, random glucose ≥200 mg/dL with symptoms, or HbA1c ≥6.5%. However, HbA1c results may be unreliable in certain conditions, such as anemia or hemoglobinopathies, and the diagnosis should be confirmed unless classic symptoms are present. Postprandial hyperglycemia is typically considered significant when glucose levels exceed 180 mg/dL two...

Urine Studies I: Urinalysis

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Urinalysis is a widely used diagnostic test that analyzes urine's physical, chemical, and microscopic characteristics. Healthcare providers use it to detect and monitor various health conditions, including renal disease, urinary tract infections (UTIs), diabetes, and metabolic or systemic disorders.Components of UrinalysisUrinalysis consists of three primary components: physical, chemical, and microscopic examination. Each provides unique insights into the urine sample and, by extension, the...

Urinary Tract Calculi III: Medical Management

Urinary Tract Calculi III: Medical Management

The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...

Urinary Tract Calculi I: Introduction

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Serum Studies: Renal Function Tests

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Related Experiment Video

Updated: Jun 13, 2026

Quantitative SERS Detection of Uric Acid via Formation of Precise Plasmonic Nanojunctions within Aggregates of Gold Nanoparticles and Cucurbit[n]uril

Quantitative SERS Detection of Uric Acid via Formation of Precise Plasmonic Nanojunctions within Aggregates of Gold Nanoparticles and Cucurbit[n]uril

Published on: October 3, 2020

Hyperuricemia.

Canadian Family Physician Medecin De Famille Canadien

|May 15, 2010

Summary

Hyperuricemia, or high uric acid levels, can harm kidneys through stones, tubule blockage, or chronic nephritis. Modest cases without symptoms are often harmless, but persistent high levels warrant medical consideration.

Area of Science:

Nephrology
Urology
Internal Medicine

Background:

Hyperuricemia results from uric acid under-excretion or over-production, which can be congenital or acquired.
High uric acid levels can manifest in several ways, impacting kidney health.
The clinical significance of varying hyperuricemia degrees is a subject of ongoing medical discussion.

Purpose of the Study:

To review the causes and consequences of hyperuricemia.
To elucidate the mechanisms by which hyperuricemia affects renal function.
To discuss the threshold for intervention in asymptomatic hyperuricemia.

Main Methods:

Literature review of studies on hyperuricemia and kidney disease.
Analysis of the pathophysiological pathways linking uric acid to renal damage.

Related Experiment Videos

Last Updated: Jun 13, 2026

Quantitative SERS Detection of Uric Acid via Formation of Precise Plasmonic Nanojunctions within Aggregates of Gold Nanoparticles and Cucurbit[n]uril

Quantitative SERS Detection of Uric Acid via Formation of Precise Plasmonic Nanojunctions within Aggregates of Gold Nanoparticles and Cucurbit[n]uril

Published on: October 3, 2020

Discussion of clinical guidelines and expert opinions on managing hyperuricemia.

Main Results:

Hyperuricemia can lead to kidney stones, acute renal failure via tubule blockage, and chronic interstitial nephritis in gout patients.
Mild, asymptomatic hyperuricemia may not significantly harm the kidneys.
The impact of persistent uric acid levels exceeding 10 mg% on kidney health remains under investigation.

Conclusions:

Hyperuricemia poses multiple risks to kidney function, including stone formation and acute or chronic renal failure.
The management threshold for asymptomatic hyperuricemia, particularly levels above 10 mg%, is a point of clinical consideration.
Further research may clarify the long-term renal effects of sustained hyperuricemia.