n-Alkylresorcinol occurrence in Mercurialis perennis L. (Euphorbiaceae)
Peter Lorenz1, Matthias Knödler, Julia Bertrams
1WALA Heilmittel GmbH, Department of Research & Development, Dorfstrasse 1, D-73087 Bad Boll/Eckwälden, Germany.
Abstract:
Investigation of the dichloromethane extracts from herbal and root parts of Mercurialis perennis L. afforded a mixture of 11 homologous n-alkylresorcinols (ARs) with saturated odd-numbered alkyl side chains (C15:0-C27:0). In addition to three predominant ARs (C19:0, C21:0 and C23:0), a number of minor ARs were identified by use of LC-MS/MS and GC-MS techniques. Among the compounds detected, four uncommon ARs with even-numbered alkyl side chain lengths were also determined. The overall AR concentration in herbal parts was 7 to 9 times higher compared to that of the roots. The results presented may open a new view on the phytochemistry and pharmacognosy of M. perennis and other members of the Euphorbiaceae family.
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