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Related Concept Videos

Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Allergic Reactions02:06

Allergic Reactions

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Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Allergic Drug Reactions01:27

Allergic Drug Reactions

Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
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Related Experiment Video

Updated: Jun 13, 2026

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
06:34

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

Published on: June 4, 2017

[Allergy diagnosis by primary care physicians].

Philippe A Eigenmann1

  • 1Unité d'allergologie adulte et enfant Service d'immunologie, HUG, 1211 Genève 14.

Revue Medicale Suisse
|May 18, 2010
PubMed
Summary

Primary care physicians can diagnose allergies using patient history and tests like skin prick tests or serum IgE measurements. Proper interpretation of results is key to avoid unnecessary treatments and dietary changes for effective allergy management.

Area of Science:

  • Immunology
  • Clinical Medicine
  • Diagnostic Procedures

Background:

  • Allergy diagnosis in primary care relies on patient history.
  • Immunoglobulin E (IgE) mediated allergies require specific diagnostic investigations.
  • Accurate interpretation of diagnostic tests is crucial for appropriate patient care.

Observation:

  • Physicians utilize patient history for initial allergy assessment.
  • Skin tests and serum IgE antibody measurements are common investigations for suspected IgE allergies.
  • Positive test results must be evaluated in the context of clinical symptoms to prevent misdiagnosis.

Findings:

  • Guidance is needed for primary care physicians to select optimal diagnostic methods.
  • Distinguishing sensitization from true allergy is essential.

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Related Experiment Videos

Last Updated: Jun 13, 2026

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
06:34

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

Published on: June 4, 2017

Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E (sIgE)
07:10

Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E (sIgE)

Published on: April 21, 2019

  • Avoiding unnecessary interventions based solely on positive tests is a clinical challenge.

    • Implications:

    • This review aims to guide primary care physicians in choosing appropriate allergy diagnostic tests.
    • Improved diagnostic strategies can lead to more accurate allergy management.
    • Evidence-based selection of diagnostic methods will enhance patient outcomes and reduce healthcare costs.