Related Experiment Video
Updated: Jun 13, 2026

A Human Fallopian Tube Model for Investigation of C. trachomatis Infections
Published on: August 11, 2012
Protective immunity to chlamydial genital infection: evidence from animal studies
Roger G Rank1, Judith A Whittum-Hudson
1Arkansas Children's Hospital Research Institute, Little Rock, AR 72202, USA. rankrogerg@uams.edu
Abstract:
In all animal models for chlamydial infection, there is strong evidence for immunity to reinfection; however, immunity is only complete (ie, preventing infection) in the short term. In the long term, animals are only partially immune (ie, they can be reinfected, but infections are usually abbreviated and less intense than the primary infection). This review will target the mechanisms responsible for long-term versus short-term immunity and explore the roles of various components of the host response in immunity to chlamydial genital infection.
Related Concept Videos
Bacterial Phylum Chlamydiae
Trichomoniasis
Sexually Transmitted Infections
Development of Immunocompetence
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...

