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Emerging drugs for the treatment of symptoms associated with autism spectrum disorders

Logan K Wink1, Martin H Plawecki, Craig A Erickson

  • 1Indiana University School of Medicine, Department of Psychiatry, Indianapolis, IN 46202, USA.

Expert Opinion on Emerging Drugs
|May 18, 2010
PubMed

Insights

Pharmacologic treatments for autism spectrum disorders (ASDs) and other pervasive developmental disorders (PDDs) are improving symptom management. Further research is needed to develop more effective and safer medications for these neurodevelopmental conditions.

Area of Science:

  • Neurobiology
  • Pharmacology
  • Developmental Neuroscience

Background:

  • Autism spectrum disorders (ASDs) and pervasive developmental disorders (PDDs) are neurodevelopmental conditions characterized by social interaction and communication impairments.
  • Increasing prevalence of ASDs necessitates effective interventions.
  • Pharmacologic agents can alleviate interfering symptoms, benefiting individuals with ASDs and their families.

Purpose of the Study:

  • To review neurobiologic research to understand autism pathophysiology.
  • To guide the development of pharmacologic treatments for ASD symptoms.
  • To evaluate current and emerging drug therapies for ASDs.

Main Methods:

  • Comprehensive review of neurobiologic research findings.
  • Analysis of safety and efficacy data for existing and investigational drugs.
  • Examination of pharmacologic agents targeting symptoms of autism and related PDDs.

Main Results:

  • Current pharmacologic treatments offer relief for some ASD symptoms.
  • Evidence supports the need for large-scale studies on commonly used medications.
  • Development of drugs with enhanced efficacy and safety profiles is crucial.

Conclusions:

  • Progress has been made in pharmacologic interventions for ASD symptoms.
  • Significant work remains to optimize treatment strategies.
  • Future research should focus on improving drug efficacy and safety.
Abstract

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