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Related Concept Videos

Peritoneal Dialysis I: Introduction and Procedure01:30

Peritoneal Dialysis I: Introduction and Procedure

Peritoneal dialysis (PD) is a procedure that facilitates the exchange of solutes, waste products, electrolytes, and excess fluid between the blood in the peritoneal capillaries and a dialysis solution introduced into the peritoneal cavity.Principles of Peritoneal Dialysis (PD)Diffusion: Waste products such as urea and electrolytes move from high concentrations in the blood to low concentrations in the dialysate across the peritoneal membrane. This mechanism is driven by the concentration...
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications01:25

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
Peritoneal Dialysis III: Nursing Management01:25

Peritoneal Dialysis III: Nursing Management

Peritoneal dialysis, or PD, utilizes the peritoneal membrane as a filter to eliminate excess fluid and waste products. Effective nursing management is essential for ensuring patient safety, preventing complications, and promoting optimal function of the peritoneal dialysis process.Assessment and MonitoringNurses must thoroughly assess the patient before, during, and after each dialysis session. Regular monitoring includes vital signs, daily weight, fluid intake and output, and laboratory values...
Drug Accumulation During Multiple Dosing: Intermittent IV Infusions01:24

Drug Accumulation During Multiple Dosing: Intermittent IV Infusions

Intermittent intravenous (IV) infusion is a method of drug administration where medications are delivered over short infusion periods followed by intervals of no drug delivery. This approach helps to prevent sustained high drug concentrations in the bloodstream, reducing the risk of adverse effects associated with prolonged exposure. Unlike continuous infusion, steady-state concentrations may not be achieved during a single dosing cycle but can be reached through repeated...
Heart Failure Drugs: Diuretics01:22

Heart Failure Drugs: Diuretics

Heart failure and kidney perfusion are interconnected in a complex way. Reduced renal perfusion and venous congestion are two significant factors that contribute to renal dysfunction in heart failure. The kidneys, primarily responsible for fluid balance in the body, are adversely affected due to compromised cardiac output and increased venous pressure. In response to reduced renal perfusion, the kidneys activate neurohumoral mechanisms to restore balance. However, these mechanisms can be...
Hemodialysis III: Nursing Management01:25

Hemodialysis III: Nursing Management

The nursing management of a patient undergoing hemodialysis includes several critical steps, starting with a thorough assessment before the procedure.Before the Hemodialysis ProcedureFirst, record the patient's vital signs—blood pressure, heart rate, respiratory rate, and temperature—to establish a baseline. This baseline is essential for detecting conditions such as hypotension that could impact the patient's response to dialysis. Document the patient's pre-dialysis weight, as this measurement...

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Related Experiment Video

Updated: Jun 13, 2026

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis
07:11

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis

Published on: July 19, 2018

Two daytime icodextrin exchanges decrease brain natriuretic peptide levels and improve cardiac functions in

Tansu Sav1, Mehmet Tugrul Inanc, Ali Dogan

  • 1Department of Nephrology, Kayseri State Hospital, Kayseri, Turkey. savtansu@gmail.com

Nephrology (Carlton, Vic.)
|May 18, 2010
PubMed
Summary

Twice daily icodextrin improved cardiac function in peritoneal dialysis patients with fluid overload. Serum brain natriuretic peptide (BNP) levels decreased, correlating with improved heart metrics, suggesting BNP monitoring utility.

Related Experiment Videos

Last Updated: Jun 13, 2026

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis
07:11

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis

Published on: July 19, 2018

Area of Science:

  • Nephrology
  • Cardiology
  • Biochemistry

Background:

  • Fluid overload is common in peritoneal dialysis (PD) patients with ultrafiltration failure.
  • Increased ultrafiltration is linked to reduced left ventricular (LV) dysfunction.
  • Serum brain natriuretic peptide (BNP) is a marker for cardiac strain.

Purpose of the Study:

  • To investigate the effect of serum BNP on cardiac function in continuous ambulatory peritoneal dialysis (CAPD) patients.
  • To determine the relationship between BNP and cardiac parameters in CAPD patients experiencing ultrafiltration failure.

Main Methods:

  • 28 CAPD patients with high membrane permeability were randomized to once or twice daily icodextrin.
  • Serum BNP and echocardiographic measurements were assessed at baseline and 8 weeks.
  • Correlations between percentage changes in parameters were analyzed.

Main Results:

  • Both groups showed significant decreases in serum BNP, LV mass, heart rate (HR), and cardiothoracic index (CTI), with improved ejection fraction (P < 0.05).
  • Twice-daily icodextrin yielded significantly better improvements in all measured parameters compared to once-daily administration (P < 0.05).
  • BNP reduction positively correlated with reductions in HR, LV mass, and blood pressure (BP).

Conclusions:

  • Twice-daily icodextrin may benefit hypervolemic CAPD patients by improving cardiac function.
  • BNP monitoring could be a valuable tool for managing these patients.