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Related Concept Videos

The Thyroid Gland01:23

The Thyroid Gland

The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
Goiter01:27

Goiter

Goiter refers to an abnormal enlargement of the thyroid gland that may appear as a diffuse goiter (uniform enlargement) or nodular (single or multiple nodules). Functionally, it is classified as nontoxic (normal/low hormone levels) or toxic (excess hormone production).PathophysiologyDiffuse thyroid enlargement typically results from prolonged stimulation by thyroid-stimulating hormone (TSH) or TSH-like agents, commonly seen in hypothyroidism or iodine deficiency. In contrast, in hyperthyroid...
Hyperthyroidism II: Pathophysiology01:27

Hyperthyroidism II: Pathophysiology

Hyperthyroidism is a hypermetabolic state caused by elevated levels of thyroid hormones, triiodothyronine (T3) and thyroxine (T4). It results from dysregulation at the thyroid, pituitary, or immune system level and affects multiple organ systems.PathophysiologyThe most common cause of hyperthyroidism is Graves’ disease, an autoimmune disorder in which antibodies, specifically thyroid-stimulating antibodies (TSAb), a subtype of TSH receptor antibodies (TRAb), bind to and activate TSH receptors...
Hyperthyroidism I: Introduction01:25

Hyperthyroidism I: Introduction

Hyperthyroidism is a type of thyrotoxicosis characterized by the thyroid gland's overproduction of the thyroid hormones triiodothyronine (T3) and thyroxine (T4). This hormone excess increases the basal metabolic rate and enhances sensitivity to catecholamines.DiagnosisDiagnosis is based on clinical features and biochemical testing. It typically shows suppressed thyroid-stimulating hormone (TSH) levels below 0.4 mIU/L, with elevated free T3 and/or T4. Additional tests, including thyroid...
Graves Disease II: Pathophysiology01:24

Graves Disease II: Pathophysiology

Graves’ disease is an autoimmune disorder characterized by the production of thyroid-stimulating immunoglobulins (TSI) that activate TSH receptors, leading to excessive synthesis and release of thyroid hormones (T3 and T4) and resulting in hyperthyroidism.Among all causes of hyperthyroidism, Graves’ disease is the most common and can happen at any age, though it is more frequent in women. It produces a hypermetabolic state with features such as weight loss, tachycardia, tremor, and heat...
Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The iodine is then...

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Related Experiment Video

Updated: Jun 13, 2026

"Sun's Seven-Step Technique" for Endoscopic En-Bloc Resection of Thyroid Cancer via the Chest-Breast Approach
07:45

"Sun's Seven-Step Technique" for Endoscopic En-Bloc Resection of Thyroid Cancer via the Chest-Breast Approach

Published on: November 28, 2025

[Thyroid adenolipoma].

Andreia Veloza1, Isabel Manita, Catarina Coelho

  • 1Serviço de Endocrinologia e Diabetes, Hospital Garcia de Orta, Almada.

Acta Medica Portuguesa
|May 18, 2010
PubMed
Summary
This summary is machine-generated.

Thyroid adenolipomas, rare benign tumors of fat and thyroid tissue, present as slow-growing neck masses. Surgical removal offers a favorable prognosis for these thyrolipomas.

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"Sun's Seven-Step Technique" for Endoscopic En-Bloc Resection of Thyroid Cancer via the Chest-Breast Approach
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An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
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Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
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Area of Science:

  • Endocrinology
  • Surgical Pathology
  • Oncology

Background:

  • Thyroid adenolipomas, also known as thyrolipomas, are uncommon benign neoplasms characterized by a mixture of mature adipose and glandular thyroid tissue.
  • The typical clinical presentation is a gradually enlarging neck mass, which can sometimes be mistaken for other thyroid pathologies.

Observation:

  • This case report details a 61-year-old female with a multinodular goiter who underwent surgery due to a suspicious fine-needle aspiration biopsy.
  • The diagnosis of adenolipoma was confirmed post-operatively, highlighting diagnostic challenges.

Findings:

  • Fine-needle aspiration biopsy showing a mixed population of adipocytes and follicular cells should raise suspicion for adenolipoma.
  • Complete surgical excision is the definitive treatment for thyroid adenolipomas, ensuring a favorable prognosis.

Implications:

  • Accurate pre-operative diagnosis of thyroid adenolipomas can be challenging, often requiring surgical confirmation.
  • Understanding the clinicopathological features of thyrolipomas is crucial for appropriate patient management and differential diagnosis.