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Updated: Jun 13, 2026
04:20
A Saline/Bipolar Radiofrequency Energy Device As an Adjunct for Hemostasis in Solid Organ Injury/Trauma
Published on: July 28, 2020
[Use of radiocolloids in orthopaedic practice.]
Summary
Radiocolloid therapy using Yttrium-90 (90Y) demonstrates superior efficacy and long-term benefits for chronic synovialitis compared to Gold-198 (198Au). Yttrium-90 offers better outcomes in managing inflammatory joint conditions.
Area of Science:
- Nuclear Medicine
- Rheumatology
- Radiopharmaceutical Therapy
Context:
- Chronic synovialitis affects patients with rheumatoid arthritis, degenerative diseases, hemophilia, posttraumatic conditions, arthropathy, and gout.
- Radiocolloid administration, specifically 198Au and 90Y, has been utilized for therapeutic purposes in joint diseases.
Purpose:
- To compare the therapeutic outcomes of radiocolloid treatments using Gold-198 (198Au) and Yttrium-90 (90Y) for chronic synovialitis.
- To evaluate the efficacy and long-term effects of these radiocolloids in a large patient cohort over a significant period.
Summary:
- A study involving 865 patients treated between 1970-1995 with 1259 radiocolloid administrations found Yttrium-90 (90Y) more effective than Gold-198 (198Au).
- Following 90Y administration, 44% experienced substantial improvement and 49% improved, with 78% showing long-term effects. 198Au showed lower efficacy rates (33% substantial improvement, 50% improvement, 27% long-term effects).
Impact:
- Yttrium-90 (90Y) radiocolloid therapy is a more effective treatment option for chronic synovialitis, offering better patient outcomes and sustained relief.
- The findings support the continued use and potential preference for 90Y over 198Au in radiosynoviorthesis for various joint pathologies.
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