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Identification of HLA-DPA1*020107 in an individual of Ugandan descent

Chris Czarnecki1, Ma Luo, Robert Brunham

  • 1National Microbiology Laboratory, Winnipeg, Manitoba, Canada.

Human Immunology
|May 18, 2010
PubMed

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Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...