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Wholemount Immunohistochemistry for Revealing Complex Brain Topography
Published on: April 5, 2012
Flat map areal topography in Macaca mulatta based on combined MRI and histology
Fahad Sultan1, Salah Hamodeh, Yusuke Murayama
1Department of Cognitive Neurology, HIH for Clinical Brain Research, Tuebingen, Germany. fahad.sultan@uni-tuebingen.de
Abstract:
Flattened representations are a useful approach to represent the convoluted complex surface of the neocortex of primates and other large-brained mammals. In this study, we compared the flattened representation of neocortical areas obtained from the recently published MRI and histology atlas of the rhesus monkey brain (Saleem KS, Logothetis NK. A combined MRI and histology atlas of the rhesus monkey brain in stereotaxic coordinates. London: Academic; 2007) with other previously published maps. Our results confirm that flat map representations are advantageous due to their ease of use and that current flat maps are well comparable to each other. Some differences arise due to different distinguishing criteria and here too flat maps can help to reveal them.

