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Updated: Jun 13, 2026

A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space
Published on: February 1, 2016
Looking for a 5-HT7 radiotracer for positron emission tomography
Julien Andriès1, Laëtitia Lemoine, Alice Mouchel-Blaisot
1Université de Lyon, Université Lyon 1, CNRS, ICBMS (UMR CNRS 5246), Lyon, France.
Abstract:
In search of a serotonin 5-HT(7) radiotracer for positron emission tomography, we developed 1-[2-[(2S)-1-(phenylsulfonyl)pyrrolidin-2-yl]ethyl]piperidin-4-yl 4-fluorobenzoate. After labeling in good yield with fluorine-18 via nitro for fluorine exchange, preliminary biological experiments with autoradiographies failed to evidence any specific 5-HT(7) receptor delineation.
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