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Computer assisted analysis of hand radiographs in infantile hypophosphatasia carriers
B N Chodirker1, D Roy, C R Greenberg
1Department of Pediatrics and Child Health, University of Manitoba, Canada.
Pediatric Radiology
|January 1, 1991
Abstract:
Hand radiographs of 49 carriers of infantile hypophosphatasia and 67 non-carriers were evaluated using two Apple IIe Computer Programs and an Apple Graphics Tablet. CAMPS (1) was used to determine the bone lengths and calculate the metacarpophalangeal profiles. A newly developed program (ADAM) was used to determine bone density based on percent cortical area of the second metacarpal. Carriers of infantile hypophosphatasia had significantly less dense bones.