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[Gastroduodenal pathology in pyelonephritis in children]
Pediatriia
|January 1, 1991
Summary
Children with pyelonephritis often have upper digestive tract issues, including Campylobacter pylori infection. Treatment should address both pyelonephritis and gastroduodenal pathology for better outcomes.
Area of Science:
- Pediatric Gastroenterology
- Infectious Diseases
- Nephrology
Background:
- Pyelonephritis, a kidney infection, can be associated with gastrointestinal complications in children.
- Upper alimentary tract lesions are frequently observed in pediatric patients with urinary tract infections.
Purpose of the Study:
- To investigate the prevalence and nature of upper alimentary tract lesions in children diagnosed with pyelonephritis.
- To identify specific pathologies, such as Campylobacter pylori infection, co-occurring with pyelonephritis in pediatric patients.
Main Methods:
- Intragastric pH-metry was performed on 91 children (aged 4-15) with pyelonephritis.
- Endoscopic examination and histological analysis of gastric and duodenal biopsy specimens were conducted.
- Campylobacter pylori presence was assessed in antral biopsy samples.
Main Results:
- Gastroduodenal pathology was diagnosed in three-quarters of the children studied.
- Campylobacter pylori was identified in the gastric antrum mucosa of 69.4% of these children.
- A significant association between pyelonephritis and upper digestive tract pathology, including H. pylori, was observed.
Conclusions:
- Children with pyelonephritis exhibit a high incidence of gastroduodenal pathology, frequently involving Campylobacter pylori.
- Integrated treatment strategies are necessary, addressing both pyelonephritis and upper alimentary tract conditions, including H. pylori eradication.
- Dietary modifications and anti-inflammatory agents are recommended alongside specific treatments for H. pylori.