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Updated: Jun 13, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Transcatheter repair of perivalvular regurgitation
Barry A Love1, Gregory W Fischer, Alexander Mittnacht
1Division of Pediatric Cardiology, Mount Sinai School of Medicine, New York, NY 10029, USA. barry.love@mssm.edu
Abstract:
Hemodynamically significant perivalvular regurgitation affects about 1.5% of all prosthetic valve implants. Reoperation carries increased risk--especially in the setting of concomitant comorbidities of left ventricular dysfunction, prior coronary artery bypass grafts, renal dysfunction, and advanced age. Transcatheter closure of the perivalvular regurgitant channel using a variety of occluders has been available for several years; however, recent improvements in technology and technique have made this therapy more effective and available to a wider group of patients. This article describes the recent advances and the state of the art of this therapy.
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