Selection of modality in continuous renal replacement therapy

Continuous hemoperfusion therapies are now widely used in critical care, and could prove to be life-saving for patients unable to receive regular hemoperfusion treatments. Unfortunately, due to the inherent difficulties in assessing the effects of treatment upon critically ill patients, the efficacy of this modality has yet to be proven. Instead of focusing exclusively on a particular form of continuous hemoperfusion or a direct comparison between the different types available, this report provides a general overview of the studies reporting on its efficacy across a wide range of conditions. The authors conclude that continuous hemoperfusion could be beneficial in some cases, but this is highly dependent upon the particular modality used.