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Advance of studies on anti-atherosclerosis mechanism of berberine
Min Wu1, Jie Wang, Long-tao Liu
1Guang' anmen Hospital, China Academy of Chinese Medical Sciences, Beijing (100053), China.
Abstract:
Coptis Chinensis is a traditional Chinese medicine herb that has the effect of clearing heat and drying dampness, purging fire to eliminate toxin. Berberine is the main alkaloid of Coptis Chinensis, and, recent researches showed that berberine had the effect of anti-atherosclerosis. This paper reviewed the anti-atherosclerosis mechanism of berberine, which may be related to regulating lipids, anti-inflammation, decompression, reducing blood sugar, and inhibiting vascular smooth muscle cell proliferation.
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