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Updated: Jun 13, 2026

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
Published on: December 18, 2016
[The use of oral lacosamide in a patient with refractory partial epileptic status]
Laura Turpín-Fenoll1, Jorge Millán-Pascual, Santiago Navarro-Muñoz
1Servicio de Neurología y Neurofisiología, Complejo Hospitalario Mancha Centro, Alcázar de San Juan, Ciudad Real, España. lturdoc@hotmail.com
Introduction:
Generalised epileptic status is a medical emergency with a well-defined therapeutic algorithm. Nevertheless, in the partial status, treatment must be tailored to each patient and the risk of intensive treatment has to be assessed. Unlike generalised epileptic status, partial status is not considered a medical emergency, which means that when it comes to choosing a type of treatment the risk-benefit ratio must be carefully evaluated bearing in mind the characteristics of each particular case.
Case Report:
A 72-year-old male with partial status secondary to an ischaemic lesion which was refractory to conventional treatment; treatment was established with lacosamide and his condition was rapidly inverted. This is the third case that has been reported of epileptic status being treated with this drug and the second in which it is employed orally.
Conclusions:
Although further research is required, lacosamide could be a good therapeutic option with few interactions and side effects.
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