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Successful treatment of hereditary factor VII deficiency presented for the first time with epistaxis in pregnancy: a
Gülşah Aynaoğlu1, Gülşen Doğan Durdağ, Batuhan Ozmen
1Ankara University School of Medicine, Department of Obstetrics and Gynecology, Ankara, Turkey. gaynaoglu@gmail.com
Objective:
To present a rare case with factor VII deficiency (FVIID) that first diagnosed during pregnancy, and to disccuss the ante-, peri- and postpartum management.
Study Design:
A case report and review of the literature.
Results:
FVIID was diagnosed for the first time in a 23-year-old pregnant woman at the 24th week of gestation due to complaint of intermittent epistaxis. She was successfully treated by ante-, peripartum and postpartum replacement of recombinant FVII (rFVII). She was uneventfully discharged on the 3rd postoperative day and referred to hematology department for further follow-up.
Conclusion:
FVIID, a rare cause of ante- and postpartum hemorrhages that may differently present by other hemorrhages (i.e.: epistaxis), can be optimally managed with replacement of rFVII.
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