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Interactions of Fox proteins with inflammatory transcription-factor pathways

Stanford L Peng1

  • 1Arthritis Research Inflammation, Autoimmunity and Transplantation Research Roche Palo Alto, LLC3431 Hillview Ave, Mailstop R7-101 Palo Alto, CA 94304, USA. stanford.peng@roche.com

Expert Review of Clinical Immunology
|May 19, 2010
PubMed
Summary

Forkhead (Fox) proteins regulate immune homeostasis. Beyond Foxp3 in regulatory T cells, other Fox proteins like Foxj1, Foxo3a, and Foxd1 are crucial for intrinsic T cell immunity by opposing inflammatory pathways.

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