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Updated: Jun 13, 2026

Isolation of Mouse Lung Dendritic Cells

Isolation of Mouse Lung Dendritic Cells

Published on: November 22, 2011

Dendritic cells in viral bronchiolitis.

Paraskevi Maggina¹, Ioannis Christodoulou, Vassiliki Papaevangelou

¹Allergy Research Centre, 2nd Paediatric Clinic, Medical School, University of Athens, 41 Fidippidou Street, Goudi, 11527 Athens, Greece. viva6mag@yahoo.com

Expert Review of Clinical Immunology

|May 19, 2010

Summary

This summary is machine-generated.

Dendritic cells (DCs) are key immune cells linking innate and adaptive immunity. This review explores their crucial role in viral infections, particularly in infant bronchiolitis and later asthma development.

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Human Lung Dendritic Cells: Spatial Distribution and Phenotypic Identification in Endobronchial Biopsies Using Immunohistochemistry and Flow Cytometry

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Published on: January 20, 2017

Area of Science:

Immunology
Virology
Pediatrics

Background:

Dendritic cells (DCs) are vital antigen-presenting cells bridging innate and adaptive immunity.
Respiratory viruses are significant causes of infant morbidity (bronchiolitis) and later asthma.
The specific role of DCs in human respiratory viral infections remains poorly understood.

Purpose of the Study:

To review current in vivo and in vitro data on the interplay between DCs and respiratory viruses.
To elucidate the function of DCs in the context of viral bronchiolitis.

Main Methods:

Literature review of in vivo and in vitro studies.
Analysis of existing data on DC function during viral respiratory infections.

Main Results:

DCs are critical for controlling viral infections.
DCs play a complex role in the pathogenesis of viral bronchiolitis.
Understanding DC involvement may offer insights into asthma development.

Conclusions:

DCs are central players in the immune response to respiratory viruses.
Further research into DC-virus interactions is needed to understand bronchiolitis and asthma.
Targeting DC functions could be a future therapeutic strategy.