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Updated: Jun 13, 2026

Intranasal Delivery of mRNA Polyplexes via Rayleigh Breakup Aerosols: An In Vitro Method for Nasal Deposition and Functional Testing
Published on: January 20, 2026
Mometasone furoate nasal spray for nasal polyposis
1Karolinska University Hospital, Department of Otorhinolaryngology and Cochlear Implants, Huddinge, SE-141 86 Stockholm, Sweden.
Abstract:
Nasal polyposis occurs in 2-4% of the general population and is associated with significant socioeconomic costs due to severe nasal/airway symptoms that impair quality of life. Nasal corticosteroids are the first-line therapy for nasal polyposis. Mometasone furoate nasal spray is effective in relieving nasal symptoms, including nasal congestion and loss of sense of smell. This is the only intranasal corticosteroid spray to be approved in the USA for the medical treatment of nasal polyposis and the only once-daily corticosteroid spray approved for the treatment of nasal polyposis in the EU. Clinical trials have shown that mometasone furoate nasal spray has a favorable safety profile with no clinically relevant interactions with other tested medications.
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