Related Experiment Video
Updated: Jun 13, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
Recent advances in pediatric asthma treatment
1Child Health, University of Aberdeen, Royal Aberdeen Children's Hospital, Foresterhill, Aberdeen AB25 2ZG, Scotland, UK. p.j.helms@abdn.ac.uk
Pediatric wheezing illnesses often resolve but pose prognosis challenges. This review updates best practices for asthma medication in children and highlights research into novel airway treatments.
Area of Science:
- Pediatric Pulmonology
- Respiratory Medicine
- Clinical Pediatrics
Background:
- Wheezing illnesses are common in young children but often self-limiting, complicating long-term management and prognosis.
- Current asthma treatments for adults lack sufficient pediatric evidence, and some pediatric wheezing syndromes are unresponsive to existing therapies.
Purpose of the Study:
- To review and update evidence-based best practices for pediatric asthma medication.
- To promote the safe and effective use of asthma treatments in children.
- To identify emerging research areas for future therapeutic strategies.
Main Methods:
- Systematic review of current literature on pediatric wheezing and asthma management.
- Analysis of evidence for established and novel therapeutic approaches.
- Synthesis of research findings on non-allergic airway changes.
Main Results:
- Significant challenges exist in predicting long-term outcomes for childhood wheezing.
- Existing asthma medications require further evaluation for pediatric efficacy and safety.
- Emerging research focuses on airway mechanisms independent of allergy.
Conclusions:
- Updated best-practice guidelines are crucial for optimizing asthma care in children.
- Novel therapeutic targets are being explored for non-allergic airway conditions.
- Future research will likely refine management strategies for pediatric respiratory illnesses.
Related Concept Videos
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Asthma-IV: Nursing Management
First, in...
Antiasthma Drugs: Leukotriene Modifiers
Leukotriene modifiers work through two distinct mechanisms:
Asthma-I: Introduction