Related Experiment Video
Updated: Jun 13, 2026

11:07
Focal Laser Ablation of Prostate Cancer: An Office Procedure
Published on: March 30, 2021
Focal therapy in prostate cancer-report from a consensus panel.
J de la Rosette1, H Ahmed, J Barentsz
1Department of Urology, AMC University Hospital, Amsterdam, The Netherlands. j.j.delarosette@amc.uva.nl
Journal of Endourology
|May 19, 2010
Summary
Experts reached consensus on focal therapy for localized prostate cancer, guiding patient selection and treatment. This agreement will facilitate future clinical trials for this innovative approach.
Area of Science:
- Oncology
- Urology
- Radiology
- Pathology
Background:
- Focal therapy is an emerging treatment for localized prostate cancer.
- Establishing consensus on its application is crucial for standardization and advancement.
Framework:
- A consensus workshop convened urologic surgeons, radiation oncologists, radiologists, and histopathologists.
- Discussions focused on case selection, therapy conduct, and outcome assessment for focal therapy.
Implementation:
- Consensus was achieved on key aspects of patient selection, including unilateral low- to intermediate-risk disease (clinical stage ≤cT2a).
- Prostate size, tumor volume, and topography are critical selection factors, influenced by ablative technology.
- Transperineal template mapping biopsies are currently the optimal method for assessing patient characteristics; MRI with advanced techniques shows promise but requires further validation.
Implications:
- The established consensus provides a foundation for future collaborative clinical trials in focal therapy for prostate cancer.
- Standardized approaches will enhance the reliability and comparability of research findings.
Related Concept Videos
Targeted Cancer Therapies
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
There are several types of targeted therapies against specific...
Treatment Resistent Cancers
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Treatment Resistant Cancers
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...

