Related Experiment Video
Updated: Jun 13, 2026

Chemical Analysis of Water-accommodated Fractions of Crude Oil Spills Using TIMS-FT-ICR MS
Published on: March 3, 2017
Analysis of triorganotin compounds in water samples by hydrophilic interaction liquid chromatography-electrospray
Tomoharu Sano1, Hiroo Takagi, Kimiyo Nagano
1Laboratory of Intellectual Fundamentals for Environmental Studies, National Institute for Environmental Studies, Tsukuba, Ibaraki 305-8506, Japan. sanotomo@nies.go.jp
Abstract:
Hydrophilic interaction liquid chromatography (HILIC)-electrospray ionization-mass spectrometry (ESI-MS) was evaluated for the analysis of tributyltin (TBT) and triphenyltin (TPT) in water samples. Separation was performed in isocratic mode on an Atlantis HILIC silica (2.1 mm x 150 mm, 5 microm) column with a mobile phase of acetonitrile-0.1% aqueous HCOOH (86:14, v/v) at a flow rate of 0.2 mL/min. Under optimum conditions, limits of detection for TBT and TPT were 10 and 20 pg injected onto the column, respectively. The extraction of triorganotin compounds from seawater samples was carried out using a polymer-based solid phase extraction cartridge of mixed modes with reversed-phase and weak anion exchange. Tributyltin-d(27) chloride and triphenyltin-d(15) chloride were used as internal standards. The relative standard deviations for the analysis were less than 4%. Using the proposed method, it was possible to analyze concentrations of TPT and TBT in seawater at ppt levels.
More Related Videos
11:00Untargeted Metabolomics from Biological Sources Using Ultraperformance Liquid Chromatography-High Resolution Mass Spectrometry (UPLC-HRMS)
Published on: May 20, 2013
09:38Single-throughput Complementary High-resolution Analytical Techniques for Characterizing Complex Natural Organic Matter Mixtures
Published on: January 7, 2019
Related Concept Videos
Electrospray Ionization (ESI) Mass Spectrometry
ESI utilizes electrical energy to transfer ions from the liquid phase of the sample into the...
Mass Spectrometry: Complex Analysis
GC–MS is a powerful hyphenated method commonly used in forensics and environmental...
High-Performance Liquid Chromatography: Types of Detectors