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[Validation of plasma creatinine measurement on UniCel DxC 600 according to LAB GTA 04 recommendation]
Denis Chianea1, Christophe Renard, Carine Garcia
1Fédération des Laboratoires, Hôpital Percy, Clamart, Fédération des Laboratoires, Hôpital du Val-de-Grâce, Paris.
Abstract:
The accreditation process, according to NF EN ISO 15189, implies a prior evaluation of the new reagent on-site for the implementation of each new assay technique. Thus, our new standardized method for determination of creatinine (non compensated method) in plasma or serum on UniCel DxC 600 (Beckman Coulter) has been tested according to LAB GTA 04 protocol. The reagent meets the quality criteria recommended by Valtec protocol, except fidelity with the low concentration standard (50 micromol/L). Besides there is no problem of results transferability with the two other techniques used in the laboratory (Jaffe compensated and enzymatic methods performed on Cobas Integra 800).
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