Related Experiment Video
Updated: Aug 12, 2026

Mouse- and Human-derived Primary Gastric Epithelial Monolayer Culture for the Study of Regeneration
Published on: May 7, 2018
[Clinico-pathogenetic aspects of peptic ulcer therapy]
Abstract:
Peptic ulcer therapy should be combined and take into consideration possible risk factors and the clinicopathogenetic aspects of the disease. The first stage involves the treatment of a relapse. It is to be carried out at hospital and to include protective regimen, diet, and agents that normalize disorders of nervous regulation, of secretory and motor functions of the stomach, endocrine shifts, drugs that relieve microcirculatory disorders and inflammatory phenomena, contributing to ulcer healing. The second stage involves reinforcement of the treatment results after the patients' discharge from hospital. The third stage involves carrying out of antirelapse measures. Such a principle of the patients' management enables reduction of the time of their stay at hospital by 6.2 days, increase of the percentage of ulcer healing from 76 to 94, reduction of the number of relapses by 2.5 times, decrease of the temporary disability by 3.4 times, and elimination of the disease complications.
More Related Videos
03:05Establishment and Evaluation of a Risk Prediction Model for Pathological Escalation of Gastric Low-Grade Intraepithelial Neoplasia
Published on: February 16, 2024
05:23Gastric Mucosa Quantitative Polymerase Chain Reaction Analysis for Detecting Helicobacter pylori and Antibiotic Resistance
Published on: March 7, 2025
Related Concept Videos
Pathophysiology of Peptic Ulcer Disease: Injurious Factors
In the antrum region, G cells secrete the gastrin hormone that binds to gastrin-cholecystokinin-B (CCK2) receptors on parietal and enterochromaffin-like (ECL) cells in the fundic glands. Simultaneously, the vagus nerve releases acetylcholine, which binds to M3...
Pathophysiology of Peptic Ulcer Disease: Mucosal Defense Factors
Peptic Ulcer Disease I: Introduction
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
Peptic Ulcer Disease IV: Management
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current medication...
Peptic Ulcer Disease I: Introduction
Peptic Ulcer Disease II: Pathophysiology