Related Experiment Video
Updated: Jun 13, 2026

03:42
Retroperitoneal Laparoscopic Debridement and Drainage for Pancreatic Abscess
Published on: March 15, 2024
Double balloon enteroscopy and acute pancreatitis.
World Journal of Gastroenterology
|May 19, 2010
Summary
Double balloon enteroscopy (DBE) allows small bowel visualization and treatment. While severe complications are rare (1-1.7%), acute pancreatitis is an uncommon risk (0.3%) possibly due to mechanical strain.
Area of Science:
- Gastroenterology
- Endoscopic Procedures
Background:
- Double balloon enteroscopy (DBE), introduced in 2001, enables comprehensive small bowel examination, biopsy, and therapeutic interventions.
- DBE has emerged as a valuable tool for evaluating small bowel pathology, offering improved diagnostic and therapeutic capabilities.
Discussion:
- Severe complications from DBE are infrequent, affecting 1-1.7% of patients.
- Acute pancreatitis is a rare but documented complication of diagnostic DBE, with an incidence of approximately 0.3%.
- Hyperamylasemia is more common post-DBE, but its direct association with acute pancreatitis is not obligatory.
Key Insights:
- The exact mechanism causing acute pancreatitis after DBE remains unclear, though mechanical stress on the pancreas or papillary region is a leading theory.
- Over 50 cases of post-DBE acute pancreatitis have been reported in medical literature.
- While DBE is generally safe, awareness of potential complications like pancreatitis is crucial for patient management.
Outlook:
- Further research is needed to elucidate the precise etiology of post-DBE pancreatitis.
- Refinement of DBE techniques may help mitigate the risk of pancreatic complications.
- Continued surveillance and reporting of complications will enhance understanding and improve patient safety in DBE procedures.
Related Concept Videos
Acute Pancreatitis I: Introduction
Acute pancreatitis is the sudden inflammation of the pancreas caused by the early activation of digestive enzymes, leading to the autodigestion of pancreatic tissue. This results in local inflammation and, in severe cases, systemic complications.EtiologyUnderstanding the underlying causes is crucial, as identifying the etiology guides treatment and anticipates complications. Acute pancreatitis can be triggered by various factors, typically grouped into the following clinical categories.Biliary...
Acute Pancreatitis I: Introduction
Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Endoscopic Procedures V: ERCP
Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
Patient...
Patient...
Acute Pancreatitis II: Clinical Manifestations and Management
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
Acute Pancreatitis II: Pathophysiology
The pathophysiology of acute pancreatitis centers on injury to pancreatic acinar cells, which initiates a cascade of harmful intracellular events.This injury leads to premature activation of trypsinogen to trypsin in the pancreas. Trypsin then activates other digestive enzymes, such as chymotrypsin, elastase, and phospholipase A2, which begin breaking down pancreatic tissue. The resulting autodigestion causes local inflammation, tissue swelling, hemorrhage, and fat necrosis.Injured acinar cells...
Chronic Pancreatitis II: Collaborative Care
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Assessment: