Filiform polyposis in the sigmoid colon: a case series

Area of Science:

• Gastroenterology
• Pathology

Background:

• Filiform polyposis is a rare condition with unclear causes.
• It is often associated with inflammatory bowel disease (Crohn's disease, ulcerative colitis), intestinal tuberculosis, or histiocytosis X.

Observation:

• Seven cases of filiform polyposis were observed.
• The polyps were primarily located in the left colon, particularly the sigmoid area.
• These cases lacked association with inflammatory bowel disease, intestinal tuberculosis, or histiocytosis X.

Findings:

• The polyps presented as multiple, finger-like, stalactite-appearing lesions.
• Histopathologic examination revealed diverse components among the different polyps and patients.
• The observed filiform polyposis in the sigmoid colon did not show a high oncogenic potential.

Implications:

• Filiform polyposis can occur without associated systemic or inflammatory conditions.
• Periodic monitoring of sigmoid colon filiform polyposis is recommended due to its potential, albeit low, for oncogenesis.
• Further research into the pathogenesis of isolated filiform polyposis is warranted.