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Mitogens and the Cell Cycle

Mitogens and the Cell Cycle

Mitogens and their receptors play a crucial role in controlling the progression of the cell cycle. However, the loss of mitogenic control over cell division leads to tumor formation. Therefore, mitogens and mitogen receptors play an important role in cancer research. For instance, the epidermal growth factor (EGF) - a type of mitogen and its transmembrane receptor (EGFR), decides the fate of the cell's proliferation. When EGF binds to EGFR, a member of the ErbB family of tyrosine kinase...

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Related Experiment Video

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Ultra-Fast Amplicon-Based Next-Generation Sequencing in Non-Squamous Non-Small Cell Lung Cancer

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EGFR TKIs for advanced NSCLC: practical questions

Roman Perez-Soler¹

¹Division of Oncology, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA.

Oncology (Williston Park, N.Y.)

|May 20, 2010

Summary

No abstract available in PubMed .

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