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Updated: Jun 12, 2026
Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
Longitudinal growth changes of the cranial base from puberty to adulthood. A comparison of different superimposition
Zuleyha Mirzen Arat1, Hakan Türkkahraman, Jeryl D English
1Department of Orthodontics, University of Ankara, Turkey. mirzenarat@hotmail.com
Objective:
To investigate the stability of cranial reference landmarks from puberty through adulthood and to compare the displacement of these landmarks among the superimposition methods of Björk, Ricketts, Steiner, and the proposed tuberculum sella-wing (T-W) reference line.
Materials And Methods:
The sample consisted of serial lateral cephalometric radiographs of 30 Class II division 1 patients taken at the pretreatment (T1; mean age, 11.98 years), posttreatment (T2; mean age, 15.32 years) and postretention (T3; mean age, 32.12 years) periods. All cephalometric radiographs were superimposed at the cranial base according to the overall superimposition methods of Björk, Ricketts, Steiner, and the T-W method. The horizontal and vertical displacements of cranial landmarks (nasion, wing, tuberculum sella, sella, basion, and pterygomaxillare) were assessed by paired t-test according to Björk's structural method. One-way analysis of variance (ANOVA) was used for comparison of the displacement of cranial landmarks among the superimposition methods.
Results:
The tuberculum sella and wing were the most stable cranial landmarks of the cranial base. The stability of sella and pterygomaxillare points were somewhat questionable. Nasion and basion were highly variable. The displacements of all cranial landmarks were similar between the Björk and T-W methods in all study periods. Most of the cranial landmarks displaced similarly in the horizontal direction among the methods. Vertically, the behaviors of the cranial landmarks were frequently different.
Conclusions:
T-W is the most similar superimposition method to Björk's structural method; thus, it is a reliable method for examining overall facial changes.
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