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Secondary Lymphoid Organs

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Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...

Primary Lymphoid Organs

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The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...

Glaucoma: Overview

Glaucoma: Overview

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Open Angle Glaucoma: Treatment

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Related Experiment Video

Updated: Jun 12, 2026

Primed Mycobacterial Uveitis (PMU) as a Model for Post-Infectious Uveitis

Primed Mycobacterial Uveitis (PMU) as a Model for Post-Infectious Uveitis

Published on: December 17, 2021

Orbital lymphoma masquerading as panuveitis.

Puneet Panda¹, Farzin Forooghian, Todd Goodglick

¹National Eye Institute, National Institutes of Health, Bethesda, Maryland, USA.

Ocular Immunology and Inflammation

|May 21, 2010

Summary

This summary is machine-generated.

Orbital mucosa-associated lymphoid tissue (MALT) lymphoma can mimic panuveitis. Effective treatment involved radiotherapy and rituximab, resolving inflammation and retinal detachment.

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Cell-Free DNA Extraction of Vitreous and Aqueous Humor Specimens for Diagnosis and Monitoring of Vitreoretinal Lymphoma

Cell-Free DNA Extraction of Vitreous and Aqueous Humor Specimens for Diagnosis and Monitoring of Vitreoretinal Lymphoma

Published on: January 12, 2024

Area of Science:

Ophthalmology
Hematology
Oncology

Background:

Orbital MALT lymphoma is a rare B-cell neoplasm.
It can present with diverse clinical manifestations, including masquerading as inflammatory conditions.

Observation:

A case of a 53-year-old female patient with unilateral panuveitis and exudative retinal detachment is presented.
The condition was refractory to standard immunosuppressive therapy.

Findings:

The patient was diagnosed with orbital MALT lymphoma.
Treatment with radiotherapy and rituximab led to the resolution of intraocular inflammation and retinal detachment.

Implications:

Orbital MALT lymphoma should be considered in the differential diagnosis of refractory unilateral panuveitis.
Combined radiotherapy and B-cell-targeted therapy show promise for managing this condition.