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Related Experiment Video

Updated: Jun 12, 2026

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart
08:49

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart

Published on: May 11, 2018

A passively controlled biventricular support device.

Nicholas Richard Gaddum1, Daniel Lee Timms, Mark John Pearcy

  • 1School of Engineering Systems and Medical Device Domain, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia. nickgaddum@gmail.com

Artificial Organs
|May 21, 2010
PubMed
Summary
This summary is machine-generated.

This study introduces a passive controller for rotary biventricular support (BiVS) systems to address pump output balancing issues. The device successfully maintained arterial pressure during simulated hemodynamic instability, showing promise for stable cardiac support.

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Last Updated: Jun 12, 2026

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Published on: August 16, 2021

Area of Science:

  • Biomedical Engineering
  • Cardiovascular Devices
  • Control Systems

Background:

  • Balancing pump outputs is a critical challenge in rotary biventricular support (BiVS).
  • The unreliability of long-term, blood-immersed pressure sensors necessitates novel control strategies.
  • Existing systems face control issues impacting long-term viability.

Purpose of the Study:

  • To develop and evaluate a novel passive control strategy for rotary BiVS systems.
  • To improve the inherent stability and reliability of biventricular support devices.
  • To emulate the native baroreceptor response using a mechanical passive controller.

Main Methods:

  • A rotary BiVS device was designed and constructed incorporating a mechanical passive controller.
  • In vitro testing was conducted using a dual-circuit hydraulic mock circulation loop.
  • Hemodynamic destabilization was simulated to assess the device's autoregulation capabilities.

Main Results:

  • The prototype successfully maintained arterial pressures during sudden induced hemodynamic destabilization.
  • The passive controller demonstrated autoregulation of pump outputs.
  • Inlet suction was observed under specific conditions of reduced venous return during simulated hypertension.

Conclusions:

  • The developed passive controller shows potential for creating inherently stable, fully passive biventricular support.
  • Further development is warranted based on promising in vitro performance.
  • The device offers a viable alternative to complex active control systems for BiVS.