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Updated: Jun 12, 2026

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One-anastomosis Gastric Bypass (OAGB) in Rats
Published on: November 10, 2018
[Gastric bypass surgery effective for morbid obesity]
Ingrid A J van Doesburg1, Wouter W te Riele, Djamila Boerma
1St. Antonius Ziekenhuis, Afd. Chirurgie, Nieuwegein, The Netherlands. i.a.j.vandoesburg@hotmail.com
Nederlands Tijdschrift Voor Geneeskunde
|May 21, 2010
Summary
Roux-en-Y gastric bypass surgery effectively treats morbid obesity, achieving significant excess weight loss and BMI reduction. The procedure demonstrated acceptable rates of surgery-related morbidity and mortality in this patient cohort.
Area of Science:
- Bariatric Surgery
- Metabolic and Endocrine Disorders
- Surgical Outcomes Research
Context:
- Morbid obesity presents significant health challenges, necessitating effective long-term management strategies.
- Roux-en-Y gastric bypass is a widely performed bariatric procedure for severe obesity.
- Evaluating surgical outcomes is crucial for refining treatment protocols.
Purpose:
- To assess the efficacy and safety of Roux-en-Y gastric bypass in patients with morbid obesity.
- To determine excess weight loss, changes in body mass index (BMI), and complication rates.
- To compare outcomes between primary and secondary bariatric surgery interventions.
Summary:
- A descriptive analysis of 290 morbidly obese patients (BMI ≥ 35-40 kg/m²) undergoing Roux-en-Y gastric bypass between 2002-2008.
- At least 1-year follow-up in 189 patients showed a median excess weight loss of 58.6% and BMI reduction of 16.2 kg/m².
- Primary surgeries yielded higher weight loss (61.4%) than secondary (53.5%), with low mortality (0.7%) and manageable complications.
Impact:
- Roux-en-Y gastric bypass is confirmed as an effective treatment for morbid obesity.
- The study provides valuable data on the long-term success and safety profile of this bariatric procedure.
- Findings support the continued use of gastric bypass surgery in managing severe obesity and its comorbidities.
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