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Updated: Jun 12, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
[Anemia and transfusion therapy: an update].
Z Madrazo-González1, A García-Barrasa, L Rodríguez-Lorenzo
1Servicio de Cirugía General y Aparato Digestivo, Hospital Universitario de Bellvitge, Barcelona, España. zoiluco@yahoo.es
Anemia is common and requires careful management. Clinicians must consider all treatment options, including blood transfusions and iron therapy, especially for critically ill patients.
Area of Science:
- Hematology
- Internal Medicine
Background:
- Anemia is a highly prevalent condition across various medical and surgical specialties.
- Effective management of anemia is crucial due to its significant clinical impact.
Purpose of the Study:
- To review the epidemiological characteristics of anemia.
- To discuss the clinical evaluation and therapeutic options for anemia.
- To emphasize anemia management in critically ill patients.
Main Methods:
- This is a review article.
- It synthesizes current knowledge on anemia epidemiology, evaluation, and treatment.
- Focuses on evidence-based therapeutic strategies.
Main Results:
- Anemia presents diverse epidemiological features.
- Clinical evaluation involves assessing its impact and causes.
- Therapeutic strategies include blood transfusions, erythropoiesis-stimulating agents, and iron therapy.
Conclusions:
- Rational use of anemia treatments, guided by clinical evidence, is essential.
- Alternative therapies to allogeneic blood transfusion should be considered.
- Optimizing anemia management, particularly in critically ill patients, is a key clinical responsibility.
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